Brindisi (Lecce), Italy

Set on a peninsula between two arms of the Adriatic Sea, Brindisi was an important port of the Roman Empire, and later for the East India Company. In the 2nd century BC the Appian Way was built, linking the port to Rome, and a column near the harbor marks the end of that famous route. It is here that in 71 BC, the gladiator Spartacus led thousands of rebel slaves in an unsuccessful escape. Today visitors find Romanesque churches, a 13th-century castle and, in the surrounding Apulia region, remains of ancient Messapian culture.